• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Thursday, October 5, 2023
  • Login
Metro City News
  • Home
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Finance/Money
  • Sports
  • Others
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
  • Home
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Finance/Money
  • Sports
  • Others
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
Metro City News
No Result
View All Result
Home Lifestyle Health & Fitness

Nanoparticles-based improved cancer drug could be in the offing

Metro City News Desk by Metro City News Desk
January 4, 2021
in Health & Fitness
Share on FacebookShare on Twitter

New Delhi (India Science Wire): A promising method for cancer treatment by using nanoparticles, with fewer side effects and more effectiveness has been developed by a multi-institutional team from the Regional Centre for Biotechnology (Haryana), Amity University (Haryana), and National Institute of Immunology (New Delhi). In this method, nanoparticles that deliver anti-cancer drugs have been developed. The results from animal studies are promising and further research is in progress for the method to be rolled out for treatment.

Docetaxel is a drug that is commonly used to treat various types of cancer including breast, colon, and lung cancer. A formulation of the drug that is approved by the United States Food and Drug Administration (FDA) is being used all over the world. However, some components in this formulation cause harmful side effects such as liver damage and difficulty in breathing. Hence, the research team sought to develop a better alternative.

RelatedPosts

Narayana Health launches their First Ever Brand Campaign ‘Take Care’

Narayana Health launches their First Ever Brand Campaign ‘Take Care’

September 30, 2023
HCG Manavata Cancer Centre, Dr. Mayuresh Virkar, Dr. Vijay Palwe, Dr. Prakash Pandit, best in cancer treatment, Dr. Raj Nagarkar, HCGMCC,

HCG Manavata Cancer Centre, Dr. Mayuresh Virkar, Dr. Vijay Palwe, Dr. Prakash Pandit, best in cancer treatment, Dr. Raj Nagarkar, HCGMCC,

September 29, 2023

“Docetaxel is not soluble in water, and it has to be dissolved in a chemical mixture such as polysorbate-80 and alcohol to make it more soluble. This suspension is approved by the FDA, and it is commonly used worldwide including in India. Besides being potent, the drug also produces severe toxic effects in the body. So, we have developed a method that reduces the toxicity of the drug and improves its efficacy” says Dr. Avinash Bajaj, one of the corresponding authors of the study.

The team has developed nanoparticles called nanomicelles for the study. These nanomicelles are extremely small in size ranging from 10 to 100 nanometers and they serve as efficient systems through which the drugs can be delivered. This drug delivery system predominantly targets only the cancerous cells, but not the normal healthy cells.

Speaking about this, Dr. Bajaj said, “The tumor tissues have leaky blood vessels. The nanomicelles that carry docetaxel get trapped in these tumor tissues and the drug gets accumulated there. Compared to the formulation that is currently used, our formulation has shown relatively higher accumulation of docetaxel in the tumor tissues than the healthy tissues which indicates its safety and efficacy”.

The research was carried out extensively on various laboratory animals such as mice, rabbits, and monkeys. They used mice as a breast cancer model and found that the nanomicelle based drug delivery system reduced the size of the tumor in mice without producing toxic effects.

“We have been granted approval for conducting our research on 16 monkeys apart from mice, rats, and rabbits. In preclinical studies with mice, we have observed that these nanomicelles retard tumor growth. Compared to FDA-approved formulation, these nanomicelles also showed an increased rate of survivability” adds Dr. Bajaj.

The team is now working on developing nanomicelles that can carry multiple drugs instead of one drug which would increase the overall efficacy of the treatment method. About this Dr. Bajaj said, “Cancer patients are undergoing different chemotherapy cycles with different drugs. Now, we are planning to develop a nanoparticle through which a combination of drugs can be delivered instead of a single drug so that several pathways in the body can be targeted at the same time. In the future, we are also planning to work on immunotherapy along with chemotherapy”.

The study was recently published in the journal Angewandte Chemie. The research team consisted of Vedagopuram Sreekanth, Animesh Kar, Sandeep Kumar, Sanjay Pal, Poonam Yadav, Yamini Sharma, Varsha Komalla, Harsh Sharma, Radhey Shyam, Ravi D Sharma, Arnab Mukhopadhyay, Sagar Sengupta, Ujjaini Dasgupta, and Avinash Bajaj.(India Science Wire)

Tags: cancer drugNanoparticles
ShareTweetShareSendSharePinSend
Previous Post

National Atomic Timescale Inaugurated

Next Post

Assam Rifles Public School, Shillong becomes the first Khelo India Sports School from North-East

Metro City News Desk

Metro City News Desk

Related Posts

Narayana Health launches their First Ever Brand Campaign ‘Take Care’
Health & Fitness

Narayana Health launches their First Ever Brand Campaign ‘Take Care’

by Metro City News Desk
September 30, 2023
HCG Manavata Cancer Centre, Dr. Mayuresh Virkar, Dr. Vijay Palwe, Dr. Prakash Pandit, best in cancer treatment, Dr. Raj Nagarkar, HCGMCC,
Health & Fitness

HCG Manavata Cancer Centre, Dr. Mayuresh Virkar, Dr. Vijay Palwe, Dr. Prakash Pandit, best in cancer treatment, Dr. Raj Nagarkar, HCGMCC,

by Metro City News Desk
September 29, 2023
Artificial Intelligence can’t replace doctors healing touch, Experts
Health & Fitness

Artificial Intelligence can’t replace doctors healing touch, Experts

by Metro City News Desk
September 21, 2023
KareXpert achieves Ayushman Bharat Digital Mission Certification, paving the way for the digital healthcare revolution
Health & Fitness

KareXpert achieves Ayushman Bharat Digital Mission Certification, paving the way for the digital healthcare revolution

by Metro City News Desk
September 13, 2023
“Dr. Anjum Shaikh’s Empowering Debut: Groundbreaking Book ‘EmpowHER: Wellness, Hygiene, and YOU’ Sets a New Standard for Women’s Health Advocacy
Health & Fitness

“Dr. Anjum Shaikh’s Empowering Debut: Groundbreaking Book ‘EmpowHER: Wellness, Hygiene, and YOU’ Sets a New Standard for Women’s Health Advocacy

by Metro City News Desk
September 5, 2023
“Empowering Women Through Innovative Healthcare: Dr. Monika Agarwal, Leading Cosmetic Gynaecologist and Laparoscopic Surgeon in Ghaziabad”
Health & Fitness

“Empowering Women Through Innovative Healthcare: Dr. Monika Agarwal, Leading Cosmetic Gynaecologist and Laparoscopic Surgeon in Ghaziabad”

by Metro City News Desk
September 4, 2023
Next Post

Assam Rifles Public School, Shillong becomes the first Khelo India Sports School from North-East

40th Indian scientific expedition to Antarctica launched

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

A “Path Showing” Conclave for Real Estate Industry by V21 Group at Pune

A “Path Showing” Conclave for Real Estate Industry by V21 Group at Pune

May 13, 2023

ZingHR now enters aggressively into the Indian SMB HRMS market with their new vertical ZingNeo

April 13, 2021
Sulatha Francis on her poetry collection titled ‘Father’s Face’

Sulatha Francis on her poetry collection titled ‘Father’s Face’

January 6, 2022

New collaboration to launch India-UK Dual Doctoral Programme

March 17, 2021
Unibox Production presents Iconic Star Gala Awards (ISGA AWARDS) has an initiative by Dushyant Sehgal that celebrated the unsung Iconic stars of the different industries

Unibox Production presents Iconic Star Gala Awards (ISGA AWARDS) has an initiative by Dushyant Sehgal that celebrated the unsung Iconic stars of the different industries

December 30, 2021

Fitness entrepreneur ‘The Yash Thakur’ blends style to bring the best out of fitness

July 30, 2021
Kingston FURY Adds AMD EXPO Certified DDR5 to Lineup

Kingston FURY Adds AMD EXPO Certified DDR5 to Lineup

October 6, 2022

Medgate Today’s MedTech Policy Mahotsav Conclave Calls for Policy Reforms, Collaborations, Innovations, and Competitiveness

June 20, 2023

Choubey Ji is back with Season 2

December 30, 2022

Invesco India Focused 20 Equity Fund NFO collects over Rs. 602 crs

October 2, 2020

Making every smile count – Roadcast launches a unique Diwali campaign to celebrate delivery personnel

October 21, 2022

IIT Delhi to establish department of energy science and engineering

May 31, 2021

Riverdale Aerovista launches “Home and Happiness” offer for Home-Seekers

May 28, 2021

Russian Universities offer good opportunities for Indian students pursuing MBBS

August 1, 2022

Co-WIN for planning, implementation, monitoring, and evaluation of COVID-19 vaccination

January 18, 2021

Shri Pashupati Kumar Paras, Union Minister for Food Processing Industries, and President RLJP addressed the party’s Tamil Nadu state and district level executive meeting held in Chennai

May 15, 2023

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Health & Fitness
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • Uncategorized
  • World

Recent News

SheThePeople to host its 9th Digital Women Awards at T-Hub, Telangana

SheThePeople to host its 9th Digital Women Awards at T-Hub, Telangana

October 4, 2023
Embrace the Journey with Kingston Technology on World Tourism Day

Embrace the Journey with Kingston Technology on World Tourism Day

October 4, 2023
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Metro City News

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Metro City News

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In